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Homocysteine Plus

$28.39

Methylation is one of the most important biochemical processes happening inside your body right now, even though most people have never heard of it. It is the process your cells use to turn genes on and off, build neurotransmitters, manage homocysteine, and support your antioxidant defenses, all working together to keep cellular function running smoothly.* When methylation runs well, so much else falls into place. When it lacks the cofactors and methyl donors it needs, the whole system can struggle.

Homocysteine Plus was built to give your methylation pathways the comprehensive nutritional support they depend on.

It is a thoughtfully formulated, eight-ingredient blend that pairs the activated, bioavailable forms of folate, B12, B6, and B2 with key methylation cofactors and antioxidant support.* From L-methylfolate (the form that works even with common MTHFR genetic variations) to methylcobalamin B12, to trimethylglycine, serine, zinc, glutathione, and pyridoxal-5-phosphate B6, every ingredient earns its place in this once-daily formula.*

Methylation is one of the most important biochemical processes happening inside your body right now, even though most people have never heard of it. It is the process your cells use to turn genes on and off, build neurotransmitters, manage homocysteine, and support your antioxidant defenses, all working together to keep cellular function running smoothly.* When methylation runs well, so much else falls into place. When it lacks the cofactors and methyl donors it needs, the whole system can struggle.

Homocysteine Plus was built to give your methylation pathways the comprehensive nutritional support they depend on.

It is a thoughtfully formulated, eight-ingredient blend that pairs the activated, bioavailable forms of folate, B12, B6, and B2 with key methylation cofactors and antioxidant support.* From L-methylfolate (the form that works even with common MTHFR genetic variations) to methylcobalamin B12, to trimethylglycine, serine, zinc, glutathione, and pyridoxal-5-phosphate B6, every ingredient earns its place in this once-daily formula.*

Frequency:

The Key Ingredients, and Why They Are In Here

L-5-MTHF (Metafolin® L-Methylfolate) is the activated form of folate that supplies methyl groups directly to the methionine cycle, working even in individuals with common MTHFR genetic variations that limit conversion of standard folic acid.*

Methylcobalamin (Vitamin B12) is the bioactive form of B12 that directly participates in the methylation reactions involved in healthy homocysteine metabolism.*

Riboflavin-5-Phosphate (Vitamin B2) is the activated form of B2 and a required cofactor for the MTHFR enzyme, supporting healthy folate utilization.*

Pyridoxine and Pyridoxal-5-Phosphate (Vitamin B6) combine both the standard and the activated forms of B6, supporting folate metabolism, transsulfuration, and the body’s production of cysteine and glutathione.*

Trimethylglycine (Betaine Anhydrous) is a methyl donor that supports the body’s BHMT pathway, a folate-independent route active in the liver and kidneys for healthy homocysteine metabolism.*

L-Serine contributes methyl groups for folate regeneration and supports the body’s production of cysteine and taurine for downstream antioxidant support.*

Zinc (as Zinc Picolinate) is a cofactor for both methionine synthase and BHMT, the enzymes involved in healthy remethylation.*

L-Glutathione (Reduced) is one of the body’s most important antioxidants, supporting cellular antioxidant balance and helping protect methylation capacity from oxidative pressure.*

Supplement Facts

Serving Size: 1 capsule. Servings Per Container: 90.

Amount per serving:

  • Vitamin B2 (as Riboflavin-5-Phosphate): 10 mg

  • Vitamin B6 (50% as Pyridoxine Hydrochloride, 50% as Pyridoxal-5-Phosphate): 30 mg

  • 5-Methyltetrahydrofolate (from 740 mcg [6S]-5-methyltetrahydrofolic acid, glucosamine salt, as Metafolin®): 400 mcg

  • Vitamin B12 (as Methylcobalamin): 400 mcg

  • Zinc (as Zinc Picolinate): 5 mg

  • Trimethylglycine (Betaine Anhydrous): 500 mg

  • L-Serine: 100 mg

  • L-Glutathione (Reduced): 50 mg

Other Ingredients: Hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, silicon dioxide.

Free from gluten, dairy, milk, casein, soy, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, corn, yeast, and sesame.

Directions: As a dietary supplement, take 1 capsule 1 or 2 times daily with meals, or as directed by your healthcare practitioner.

Warning: If you experience any fatigue or adverse reaction, reduce the dose or discontinue use. Variations in product color may occur. Keep in a cool, dry place, tightly capped.

If you are pregnant or nursing, are taking prescription medications, or have an ongoing health concern, please consult your healthcare practitioner before use.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.